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priligy dapoxetina 30mg nos eua The inducible homozygous I ER SP C I73T I73T Flp line provided a sweet spot by permitting postnatal, AT2 cell specific expression of mutant Sftpc I73T mRNA in relative amounts 60 70 of WT approximating those in affected humans carrying a single mutant SFTPC allele Figure 3B while developing translationally relevant features of IPF, including a histology with some UIP features and expression of IPF related chemokines, cytokines, and putative biomarkers